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1.
Soc Sci Med ; 345: 116662, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38364726

RESUMO

Intensive care unit (ICU) professionals engage in ethical decision making under conditions of high stakes, great uncertainty, time-sensitivity and frequent irreversibility of action. Casuistry is a way by which actionable knowledge is obtained through comparing a patient case to previous cases from experience in clinical practice. However, within the field of study as well as in practice, evidence-based medicine is the dominant epistemic framework. This multiple case study evaluated the use of casuistic reasoning by intensive care unit (ICU) professionals during moral case deliberation. It took place in two Dutch hospitals between June 2020 and June 2022. Twentyfive moral case deliberations from ICU practice were recorded and analyzed using discourse analysis. Additionally, 47 interviews were held with ICU professionals who participated in these deliberations, analyzed using thematic analysis. We found that ICU professionals made considerable use of case comparisons when discussing continuation, withdrawal or limitation. Analogies played a role in justifying or complicating moral judgements, and also played a role in addressing moral distress. The language of case-based arguments is most often not overtly normative. Rather, the data shows that casuistic reasoning deals with the medical, ethical and contextual elements of decisions in an integrated manner. Facilitators of MCD have an essential role in (supporting ICU professionals in) scrutinizing casuistic arguments. The data shows that during MCD, actual reasoning often deviated from principle- and rule-based reasoning which ICU professionals preferred themselves. Evidence-based arguments often gained the character of analogical arguments, especially when a patient-at-hand was seen as highly unique from the average patients in the literature. Casuistic arguments disguised as evidence-based arguments may therefore provide ICU professionals with a false sense of certainty. Within education, we should strive to train clinicians and ethics facilitators so that they can recognize and evaluate casuistic arguments.


Assuntos
Casuísmo , Princípios Morais , Humanos , Resolução de Problemas , Pesquisa Qualitativa , Estudos Longitudinais
2.
J Int Bioethique Ethique Sci ; 33(2): 41-50, 2023.
Artigo em Francês | MEDLINE | ID: mdl-36894339

RESUMO

The digital transformation of justice is the vector of profound change for the litigant. If it can have advantages (speed, accessibility, efficiency), it also presents risks, whether it is the dehumanization of justice or the risk of a digital divide. The study seeks to highlight all the ambivalence of the digital transition in the light of the diversity of litigants.


Assuntos
Casuísmo , Justiça Social , Humanos
3.
Med Health Care Philos ; 26(1): 69-84, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36350535

RESUMO

Casuistry, which involves analogical reasoning, is a popular methodological approach in bioethics. The method has its advantages and challenges, which are widely acknowledged. Meta-philosophical reflection on exactly how bioethical casuistry works and how the challenges can be addressed is limited. In this paper we propose a framework for structuring casuistry and analogical reasoning in bioethics. The framework is developed by incorporating theories and insights from the philosophy of science: Mary Hesse's ideas on horizontal and vertical relations in analogical reasoning in the sciences, Paul Bartha's articulation model of analogical reasoning and Daniel Steel's insights on mechanism-based extrapolation in biomedical research. Adopting our framework results in two practical benefits: it sets methodological standards for analogical reasoning and enables us to compare and evaluate diverging lines of analogical reasoning in a systematic way. Adopting the framework also has theoretical benefits: it helps to understand how analogical reasoning can have moral normativity; it pinpoints exactly where moral principles or theories enter analogical reasoning; and it helps to understand why casuistry is an attractive method in bioethics and in applied ethics more generally.


Assuntos
Bioética , Humanos , Princípios Morais , Casuísmo , Análise Ética , Teoria Ética
4.
Artigo em Inglês | MEDLINE | ID: mdl-36011475

RESUMO

The corpus callosum plays a vital role in brain function. In particular, in the trunk of the corpus callosum, in the course of various diseases, there may be temporary, reversible changes (reversible splenial lesion syndrome (RESLES)), as well as partially reversible and irreversible changes. This article discusses the differentiation of RESLES and other conditions with changes in the corpus callosum lobe, as well as the accompanying clinical symptoms. Moreover, a case report of a patient in whom the above changes appeared in the nuclear magnetic resonance (NMR) image is presented. A 20-year-old patient with the diagnosis of Ehlers-Danlos syndrome type VI was admitted to the psychiatric ward in an emergency because of psychomotor agitation, refusal to take food and fluids, delusional statements with a message, grandeur, and auditory hallucinations. In the performed magnetic resonance imaging (MRI) of the brain, the corpus callosum non-characteristic in T2-weighted images revealed a hyperintensive area, which was significantly hyperintensive in diffusion magnetic resonance (DWI) sequences and in apparent diffusion coefficient (ADC) sequences with reduced signal intensity and no signs of bleeding. The hypothesis of subacute ischemic stroke of the corpus callosum was presented. In the control MRI of the brain, changes in the corpus callosum completely regressed, thus excluding an ischemic etiology and favoring the diagnosis of RESLES. During hospitalization, the patient experienced significant fluctuations in mental status, with the dominant symptoms typical of the paranoid syndrome in the form of disturbances in the course and structure of thinking and perception, and a clear and stable improvement was obtained after the administration of long-acting intramuscular olanzapine. Taking into account the clinical and radiological picture, the age of the episode, the rapidity of the disease development, the persistence of its clinical symptoms after the withdrawal of radiological changes in the brain NMR image, as well as the significant improvement in the clinical condition after the introduction of antipsychotic drugs, the final diagnosis was made of schizophrenia.


Assuntos
Encefalopatias , Adulto , Encefalopatias/diagnóstico , Casuísmo , Corpo Caloso/diagnóstico por imagem , Corpo Caloso/patologia , Imagem de Difusão por Ressonância Magnética/efeitos adversos , Humanos , Imageamento por Ressonância Magnética/efeitos adversos , Síndrome , Adulto Jovem
5.
Semina cienc. biol. saude ; 43(2): 209-222, jul./dez. 2022. ilus, tab
Artigo em Português | LILACS | ID: biblio-1426364

RESUMO

Esta pesquisa buscou analisar os casos de intoxicações por organofosforados e carbamatos, presentes em agrotóxicos e pesticidas, registrados na base de dados do Centro de Informação e Assistência Toxicológica do Paraná (CIATox/PR). Trata-se de estudo retrospectivo em que foram avaliadas variáveis sociodemográficas e clínicas relacionadas à intoxicação, à forma de exposição, à causa e ao desfecho. Para a análise estatística foram utilizados testes de Kolmogorov-Smirnov, Shapiro-Wilk, Qui-Quadrado e Teste Exato de Fisher, considerando p<0,05. A amostra foi composta por 426 casos, sendo 218 (51,2%) mulheres. O principal agente foi raticida clandestino em 278 (65,2%) pacientes. A principal circunstância das intoxicações foi tentativa de suicídio com 293 (68,8%) casos. Houve predominância de exposição via oral (89,9%) e zona urbana em 349 (81,9%) casos, a maioria considerados leves (52,6%) e assistidos em serviços médicos (66,4%). Cerca de 327 (76,8%) indivíduos apresentavam manifestações clínicas. O tempo decorrido entre a exposição e o contato com o CIATox/PR foi maior nos casos considerados graves (p= 0,041). A atropina foi utilizada em 94 (49%) pacientes intoxicados por carbamatos, em 31 (33,3%) por organofosforados e em 84 (59,6%) por outros inibidores da colinesterase não especificados. Duas mulheres e um adolescente apresentaram desfecho fatal, tendo em comum a ingesta intencional de "chumbinho". A casuística predominante nesta série histórica foi paciente do sexo feminino, faixa etária adulta, residente na região metropolitana, exposta a agrotóxico por via oral, sintomática, classificada como gravidade leve, sem necessidade de atropina, contudo ocorreram três casos com desfecho para o óbito.


This research aimed to analyze the cases of poisoning by organophosphates and carbamates, present in agrochemicals and pesticides, registered in the database of the Information and Toxicological Assistance Center of Paraná (CIATox/PR). This is a retrospective study in which sociodemographic and clinical variables related to intoxication, form of exposure, cause and outcome were evaluated. For the statistical analysis, the Kolmogorov-Smirnov, Shapiro-Wilk, Chi-Square and Fisher's Exact Test were used, considering p<0.05. The sample consisted of 426 cases, 218 (51.2%) of which were women. The main agent was clandestine rodenticide in 278 (65.2%) patients. The main circumstance of intoxication was a suicide attempt with 293 (68.8%) cases. There was a predominance of oral exposure (89.9%) and urban areas in 349 (81.9%) cases, most considered mild (52.6%) and assisted in medical services (66.4%). About 327 (76.8%) individuals had clinical manifestations. The time elapsed between exposure and contact with CIATox/PR was longer in cases considered severe (p=0.041). Atropine was used in 94 (49%) patients intoxicated by carbamates, in 31 (33.3%) by organophosphates and in 84 (59.6%) by other unspecified cholinesterase inhibitors. Two women and one teenager had a fatal outcome, having in common the intentional ingestion of "chumbinho". The predominant casuistry in this historical series was a female patient, adult age, living in the metropolitan region, exposed to pesticides orally, symptomatic, classified as mild severity, without the need for atropine, however, there were three cases with an outcome of death.


Assuntos
Humanos , Masculino , Feminino , Organofosfatos , Intoxicação , Carbamatos , Inibidores da Colinesterase , Colinesterases , Agroquímicos , Casuísmo , Rodenticidas
6.
MMW Fortschr Med ; 164(3): 41, 2022 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-35146675
7.
MMW Fortschr Med ; 164(3): 47, 2022 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-35146679
8.
MMW Fortschr Med ; 164(3): 43, 2022 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-35146677
9.
Clin Ter ; 173(1): 56-63, 2022 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-35147655

RESUMO

ABSTRACT: Medical use of prescription opioids has steadily increased since the 1990s, particularly in the U.S.A. and Canada, along with abuse of these substances and significant increases in rates of addiction and death related to prescription opioids. The American authorities speak of an "addiction epidemic" and are launching a series of countermeasures to better address the problem. In Europe, there is an increasing use of prescription opioids and related problems, but the European context is much less dramatic than the American and Canadian ones. Never-theless, based on the data, it cannot be ruled out that a similar crisis will occur on the Old Continent. The aim of this study is to analyze the Italian context to better understand whether there is a possibility of an addiction epidemic. Twenty-four cases of death of people under treatment with pre-scription opioids have been retrospectively analyzed. Toxicological samples were collected with routine methods during the autopsy, followed by systematic screening for substances by diverse methods. Volatile compounds were identified using gas chromatography-flame ionization detection (GC-FID). Medical drugs and drugs of abuse were identified via the use of gas chromatography-mass spectrome-try (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS-MS). Of a total of 24 subjects, 14 died due to an overdose of Tramadol, while 7 died due to an overdose of Buprenorphine and 3 dues to a Fentanyl overdose. The most used drug was Tramadol. Histological examination was performed with hematoxylin/eosin staining, though no significant findings emerged apart from widespread edema and focal sclerosis of the myocardium, and interstitial and alveolar edema of the lungs. Our data show that attention must be paid to prescription opioids. European institutions, as soon as possible, must implement preventive measures that avoid the recurrence of the North American situation.


Assuntos
Analgésicos Opioides , Casuísmo , Analgésicos Opioides/efeitos adversos , Canadá , Humanos , Prescrições , Estudos Retrospectivos , Estados Unidos
10.
HEC Forum ; 32(3): 211-226, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32152871

RESUMO

The article is dedicated to the application questions of a case study method known as casuistry. In its long tradition, it focuses on an influential variant of the early modern period and reconstructs its functionality. In the course of reading recent receptions, it is noted that some studies speak of a "casuistic revival" in moral case deliberation in health care. As a result of this revival, casuistry has been modified in such a way that it guides case discussions in practice with the help of a tripartite methodology (morphology, taxonomy, and kinetics). However, as it turns out, casuistry, a case comparison method of ethical judgement based on reasoning logic, is less suitable for moral case deliberations in direct patient care. This stems from the fact that casuistry is a detailed procedure of ethical learning beneficial to institutionalized ethics committees or similar forms of ethics consultation in health care.


Assuntos
Casuísmo , Teoria Ética , Ética Médica , Humanos
11.
An. venez. nutr ; 33(2): 149-153, 2020.
Artigo em Espanhol | LILACS, LIVECS | ID: biblio-1392966

RESUMO

El trabajo plantea la necesidad de abordar el hambre oculta a partir de los retos alimentarios y la casuística socioeconómica que la explican. Se analizan los usos que ha recibido desde la historia de la población y su asociación con los síndromes de miseria, atraso social y pauperización, Así como la nueva dimensión que ha adquirido con la emergencia de la pandemia de obesidad y la doble carga de la malnutrición y el sobrepeso. Tanto las lecciones de la historia, como el reto que representan los más de 2.000 millones de seres humanos afectados por el hambre oculta, muestran que para superarla, más allá de suplementar el déficit de micronutrientes, hay que corregir las desigualdades sociales ante la disponibilidad de alimentos y otras necesidades básicas(AU)


The work raises the need to address hidden hunger based on food challenges and the socioeconomic casuistry that explain it. Are analysed the uses it has received from the history of the population and its association with the syndromes of misery, social backwardness and pauperization. As well as the new dimension that it has acquired with the emergence of the obesity pandemic and the double burden of malnutrition and overweight. Both the lessons of history, and the challenge posed by the more than 2 billion human beings affected by hidden hunger, show that to overcome it, beyond supplementing the deficit of micronutrients, it is necessary to correct social inequalities regarding the availability of food and other basic necessities(AU)


Assuntos
Fatores Socioeconômicos , Desnutrição , Fome Oculta , Pobreza , Doenças Transmissíveis , Micronutrientes , Casuísmo , Sobrepeso , Alimentos , Obesidade
12.
Rev. argent. mastología ; 38(139): 17-28, oct. 2019. graf
Artigo em Espanhol | LILACS | ID: biblio-1116505

RESUMO

Objetivo El objetivo del presente trabajo es analizar las características de las pacientes con antecedente de cáncer de mama que desarrollaron metástasis ováricas. Material y método Se identificaron casos entre enero de 2000 y diciembre de 2017. Se estudiaron las siguientes variables: edad al inicio y edad de la aparición de la metástasis ovárica; tipo histológico; perfil ihq del tumor mamario y anexial; estadio; uni o bilateralidad; tratamiento; latencia entre primario de mama y secundarismo en ovario; presentación; diagnóstico presuntivo preoperatorio; tipo de cirugía: tratamiento posterior; sle y sg. Resultados Se identificaron 17 casos. La incidencia de metástasis ováricas de cáncer de mama fue del 0,3%. El 82% se presentó en premenopáusicas. En cuanto al tipo: 50% fueron ductales, 43,7% lobulillares y 6,2% ductolobulillares. El perfil inmunohistoquímico fue: 62,5% Luminales B y 40% Luminales A. Todas las pacientes presentaban otros sitios de metástasis a distancia. El 62,5% fueron bilaterales y el 68,7% menores de 10 cm. La inmunohistoquimica demostró que el 53,3% modificó sus características. El tiempo de latencia entre ambos eventos, definida como punto de corte antes o después de los 5 años del primario, resultó en una diferencia marcada con sobrevida promedio de 88,5 meses para las primeras y de 154,4 meses para las segundas, pero no resultó estadísticamente significativa. Conclusiones La metástasis ovárica de cáncer mamario es un evento infrecuente. Suele aparecer en pacientes jóvenes premenopáusicas. El tipo histológico más frecuente es el lobulillar y el perfil molecular predominante es el Luminal B. La aparición de masas anexiales bilaterales sólidas o sólido-quísticas menores de 10 cm en pacientes con enfermedad diseminada debe hacer sospechar este diagnóstico


Objective Analyze the characteristics of patients with a history of breast cancer who developed ovarian metastases. Materials and method Identification of cases between January and December of 2017. Variables studied: age at onset and of the appearance of ovarian metastasis; histological type; ihc profile of breast and adnexal tumor; stage; unit or bilaterality; treatment; latency between primary breast and ovarian secondary; presentation; preoperative diagnosis; type of surgery; subsequent treatment; les and sg. Results 17 cases identified. The incidence of ovarian metastases from breast cancer was 0.3%, 82% premenopausal. 50% were ductal, 43.7% lobulillar and 6.2% ductolobulillar. The molecular profile was 62.5% Luminal A and 40% Luminal B. All the patients presented other sites of distant metastasis. 62.5% were bilateral and 68.7% were less than 10 cm. Immunohistochemistry showed that 53.3% modified its characteristics. The time elapsed between events, defined as a cut-off point before or after 5 years of the primary, resulted in a marked difference with average survival of 88.5 months for the first and 154.4 months for the second, but not statistically significant. Conclusions Ovarian metastasis of breast cancer is an infrequent event. It usually appears in young premenopausal patients. Lobular histological type and Luminal B molecular profile are predominant. The appearance of adjoining or more solid masses smaller than 10 cm in patients with disseminated disease should raise suspicion this diagnos


Assuntos
Ovário , Neoplasias da Mama , Casuísmo , Metástase Neoplásica
13.
J Eval Clin Pract ; 25(6): 962-969, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31309663

RESUMO

Nineteenth-century American philosopher Charles Sanders Peirce offered a picture of the scientific method that can be fruitfully applied to the practice of medical diagnosis. Physicians can use this framework to become more self-consciously aware of what they are doing when they diagnose medical conditions, and they can also learn more about the potential pitfalls of communication between physicians and their patients.


Assuntos
Tomada de Decisão Clínica , Diagnóstico , Inteligência Emocional , Processos Mentais , Relações Médico-Paciente/ética , Padrões de Prática Médica/ética , Avaliação de Sintomas , Casuísmo , Competência Clínica , Tomada de Decisão Clínica/ética , Tomada de Decisão Clínica/métodos , Humanos , Habilidades Sociais , Avaliação de Sintomas/ética , Avaliação de Sintomas/métodos , Avaliação de Sintomas/psicologia
14.
J Eval Clin Pract ; 25(6): 985-990, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31087718

RESUMO

OBJECTIVE: In this article, we offer an extended critical review of a new conception of bioethics, presented by Darlei Dall'Agnol, in the book Care and Respect in Bioethics. METHODS: Critical philosophical analysis of background assumptions of a new approach to bioethics, enriched with critical discussion of related philosophical literature. RESULTS: In Care and Respect in Bioethics, through an approach filled with hard cases, Dall'Agnol argues that the metaethics of respectful care has theoretical advantages over the intuitionist metaethics of principlism and the particularism of casuistry, offering an original comprehensive approach that crosses the three dimensions of ethical inquiry: metaethical, normative, and applied ethics. CONCLUSIONS: Dall'Agnol offers an insightful and persuasive account of how the single attitude of respectful care can express practical moral knowledge in healthcare. In this paper, we evaluate, criticize, and suggest refinements. One of them concerns Dall'Agnol's interpretation about Stephen Darwall's views on care and respect as two attitudes supported, respectively, by a third- and a second-personal moral point-of-view. Other is about the Dall'Agnol's Wittgensteinian description of the moral language-games of Clinical Bioethics, adding to the approach the "language-game of rights."


Assuntos
Bioética , Teoria Ética , Assistência ao Paciente , Respeito , Atitude , Casuísmo , Humanos , Assistência ao Paciente/ética , Assistência ao Paciente/psicologia , Filosofia Médica , Ética Baseada em Princípios
15.
Acta bioquím. clín. latinoam ; 52(3): 355-360, set. 2018. tab
Artigo em Espanhol | LILACS | ID: biblio-973460

RESUMO

El diagnóstico presuntivo de la equinococosis quística (EQ) se basa en estudios clínicos e imagenológicos, en particular aquellos que aplican ultrasonido, en datos epidemiológicos, y se confirma con la serología específica. En las zonas endémicas rurales, donde los procedimientos imagenológicos no siempre se encuentran disponibles, al igual que la serología convencional debido a la falta de laboratorios suficientemente equipados, las pruebas de diagnóstico rápido (TDRs) pueden ser una herramienta de gran utilidad. Se evaluó aquí la precisión diagnóstica de VIRAPID® Hidatidosis (Vircell, España), comparado con dos métodos comerciales usados frecuentemente en este laboratorio, para el diagnóstico de la Hidatidosis: HIDATEST (Laboratorio Lemos, Argentina) y ELISA IgG Echinococcus (Vircell, España). El análisis se realizó sobre 224 muestras de igual número de pacientes; 48 (21,4%) pertenecían a pacientes con quistes probablemente hidatídicos, mientras que 10 (4,5%) a pacientes con quistes no parasitarios. Se agregaron a ellos, 166 (74,1%) muestras que resultaron previamente negativas en la casuística de este laboratorio. Para los tres métodos antes mencionados, la concordancia entre los resultados obtenidos fue evaluada por el estadístico Kappa, donde en todos los casos pudo apreciarse un grado de acuerdo casi excelente. La sensibilidad y especificidad de VIRAPID fueron de 94,1%, 98,9%, ELISA 90,6%, 99,4% e HIDATEST 96,0%, 96,2%, respectivamente. Los TDRs para hidatidosis pueden ser útiles en aquellos entornos con escasos recursos para establecer la certeza diagnóstica. La prueba VIRAPID® Hidatidosis demostró tener un muy buen rendimiento, aunque sería interesante evaluar la sensibilidad del test en presencia de quistes inactivos, lo cual, se supone podría plantear problemas para el diagnóstico.


The presumptive diagnosis of cystic echinococcosis (EQ) is based on clinical and imaging studies, particularly those that apply Ultrasound, in epidemiological data, and is confirmed with specific serology. In rural endemic areas, where imaging procedures are not always available, as with conventional serology due to the lack of sufficiently equipped laboratories, rapid diagnostic tests (TDRs) can be a very useful tool. The diagnostic accuracy of VIRAPID® Hydatidosis (Vircell, Spain) was evaluated here, compared with two commercial methods frequently used in the Laboratory, for the diagnosis of Hydatidosis: HIDATEST (Laboratorio Lemos, Argentina) and ELISA IgG Echinococcus (Vircell, Spain). The analysis was performed on 224 samples from the same number of patients; 48 (21.44%) belonged to patients with probable hydatid cysts, while 10 (4.46%) belonged to patients with non-parasitic cysts. A total of 166 (74.10%) samples that were previously negative in the casuistry of our Laboratory were added. For the three methods mentioned above, the agreement between the results obtained was evaluated by the Kappa statistics, where in all the cases an almost excellent degree of agreement could be appreciated. The Sensitivity and Specificity of VIRAPID® was 94.12%, 98.88%, ELISA 90.57%, 99.44% and HIDATEST 96.00%, 96.17%, respectively. TDRs for hydatidosis may be useful in settings with limited resources to establish diagnostic certainty. The VIRAPID® test showed a very good performance, although it would be interesting to evaluate the sensitivity of the test in the presence of inactive cysts, which can pose problems for the diagnosis.


O diagnóstico presuntivo de equinococose cística (EQ) baseia em estudos clínicos e de imagem, em particular aqueles que aplicam ultrasom, em dados epidemiológicos, e é confirmado com a sorologia específica. Em áreas endêmicas rurais, onde os procedimentos de imagens nem sempre estão disponíveis, como acontece com a sorologia convencional devido à falta de laboratórios suficientemente equipamentados, os testes de diagnóstico rápido (TDRs) podem ser uma ferramenta de grande utilidade. A precisão do diagnóstico de VIRapid® hidatidose (Vircell, Espanha) foi avaliada aqui, em comparação com dois métodos comerciais frequentemente usados neste laboratório, para o diagnóstico de Hidatidose: HIDATEST (Laboratório Lemos, Argentina) e ELISA IgG Echinococcus (Vircell, Espanha). A análise foi realizada em 224 amostras do mesmo número de pacientes; 48 (21,4%) pertenciam a pacientes com cistos provavelmente hidatídicos, enquanto 10 (4,5%) pertenciam a pacientes com cistos não parasitários. Adicionaram-se a eles 166 (74,1%) amostras que resultaram previamente negativas na casuística desse Laboratório. Para os três métodos citados acima, a concordância entre os resultados obtidos foi avaliada pela estatística Kappa, onde em todos os casos um grau de concordância quase excelente pôde ser apreciado. Sensibilidade e especificidade de VIRapid® foi de 94,1%, 98,9%, ELISA 90,6%, 99,4% e HIDATEST, 96,0% e 92,6%, respectivamente. Os TDRs para hidatidose podem ser úteis em ambientes com recursos limitados para estabelecer a certeza diagnóstica. O teste VIRAPID® Hidatidose mostrou ter desempenho muito bom, apesar de que seria interessante avaliar a sensibilidade do teste em presença de cistos inativos, o que se supõe pode causar problemas para o diagnóstico.


Assuntos
Equinococose , Equinococose/diagnóstico , Métodos , Sorologia , Ultrassom , Cromatografia de Afinidade , Cistos , Casuísmo , Testes Diagnósticos de Rotina , Echinococcus , Eficiência , Recursos em Saúde
16.
J Bioeth Inq ; 15(2): 231-242, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29520736

RESUMO

In the traditions of narrative ethics and casuistry, stories have a well-established role. Specifically, illness narratives provide insight into patients' perspectives and histories. However, because they tend to see fiction as an aesthetic endeavour, practitioners in these traditions often do not realize that fictional stories are valuable moral sources of their own. In this paper I employ two arguments to show the mutual relationship between bioethics and fiction, specifically, science fiction. First, both discourses use imagination to set a scene and determine a perspective. Second, bioethics and science fiction share the family resemblance of expressing moral beliefs. I then consider how understanding bioethics and science fiction as interrelated discourses can be the basis of a methodology for inquiry into relational autonomy in the context of biotechnologies and medicine. As an example of this methodology, I analyse Fay Weldon's novel The Cloning of Joanna May (1989).


Assuntos
Bioética , Clonagem de Organismos , Análise Ética , Ética Médica , Medicina na Literatura , Reprodução , Biotecnologia , Casuísmo , Humanos , Imaginação , Literatura Moderna , Princípios Morais , Narração
17.
Issues Law Med ; 32(2): 143-172, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29108140

RESUMO

Albert Jonsen and Stephen Toulmin have argued that the best way to resolve the complex issues in medical settings is to focus on the actual details of cases and then determine what to do in the given cases. This approach to medical decision-making, labeled "casuistry," has met with much criticism. In response, Carson Strong has attempted to save much of Jonsen and Toulmin's version of casuistry. This analysis reveals that Strong's recent salvage efforts fail to deflect the major criticisms. The upshot of this analysis is that Jonsen and Toulmin's version of casuistry is not an appropriate framework from which to resolve complex issues in clinical settings.


Assuntos
Casuísmo , Tomada de Decisão Clínica , Análise Ética , Tomada de Decisões , Ética Médica
18.
Theor Med Bioeth ; 37(5): 417-31, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27639870

RESUMO

This essay concerns itself with the methodology of practical ethics. There are a variety of methods employed in ethics. Although none have been firmly established as dominant, it is generally agreed that casuistry, or the case-based method, is one important strategy commonly used for resolving ethical issues. Casuists compare the case under consideration to a relevantly similar (analogous) precedent case in which judgements have already been made, and they use these earlier judgements to determine the proper resolution of the present case. In this article, I try to provide a better understanding of the nature of contemporary casuistry. To accomplish this, I explain (in the first section) the basic features of casuistic reasoning. The second section focuses on the logic of casuistry. By assessing casuistic reasoning from the logical viewpoint, casuistry can be reconstructed as a logically correct method of reasoning. The third section looks at casuistry from the epistemic point of view and investigates the justificatory force of casuistic reasoning. Finally, in the fourth section, I show the usefulness of formal casuistry.


Assuntos
Casuísmo , Ética Médica , Análise Ética , Teoria Ética , Humanos , Lógica
19.
Theor Med Bioeth ; 36(6): 373-89, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26576963

RESUMO

This article elaborates on the relation between ethical casuistry and common law reasoning. Despite the frequent talk of casuistry as common law morality, remarks on this issue largely remain at the purely metaphorical level. The article outlines and scrutinizes Albert Jonsen and Stephen Toulmin's version of casuistry and its basic elements. Drawing lessons for casuistry from common law reasoning, it is argued that one generally has to be faithful to ethical paradigms. There are, however, limitations for the binding force of paradigms. The most important limitations--the possibilities of overruling and distinguishing paradigm norms--are similar in common law and in casuistry, or so it is argued. These limitations explain why casuistry is not necessarily overly conservative and conventional, which is one line of criticism to which casuists can now better respond. Another line of criticism has it that the very reasoning from case to case is extremely unclear in casuistry. I suggest a certain model of analogical reasoning to address this critique. All my suggestions to understand and to enhance casuistry make use of common law reasoning whilst remaining faithful to Jonsen and Toulmin's main ideas and commitments. Further developed along these lines, casuistry can appropriately be called "common law morality."


Assuntos
Casuísmo , Princípios Morais , Valores Sociais , Temas Bioéticos , Diversidade Cultural , Teoria Ética , Ética Médica , Humanos
20.
Cuad Bioet ; 26(87): 267-77, 2015.
Artigo em Espanhol | MEDLINE | ID: mdl-26378599

RESUMO

As is well known, in the field of Biomedical Ethics some methodological proposals have been put forward. They try to provide some guidelines in order to take proper decisions. These methodologies are quite useful insofar as they supply reasons for action, but they are essentially insufficient. In fact, taking a good decision requires a special skill that goes beyond sheer technique, and this skill is traditionally called practical wisdom. Not in the usual and more outlying sense of sheer caution, but in the more central one of phronesis or prudentia. Although it is not a new notion, it usually appears blurred in biomedical decision-making theory, playing the wrong role, or in a marginal or indefinite way. From this postulate, we will try to make a double analysis. First, we will try to show the need for a proper understanding of the core role that phronesis plays in decision making. Second, we will try to get the original meaning of Aristotelian phronesis back. For reasons of space, in this paper the second question will be just partially addressed.


Assuntos
Bioética , Pesquisa Biomédica/ética , Bioética/história , Casuísmo , Tomada de Decisões/ética , Europa (Continente) , História Antiga , História Medieval , Humanos , Julgamento , Filosofia/história , Virtudes
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